Hi.
MS Server 2022 isn't supported as it was released after PB 2021 was released. And you must be aware that even windows server 2019, 2016 & 2012 R2 are only supported for powerbuilder runtime. Not for the IDE.
From PB 2021 Installation Guide (System Requirements - - Installation Guide (appeon.com)):
Supported by PowerBuilder IDE and Runtime:
Windows 8.1 32-bit or 64-bit
Windows 10 32-bit or 64-bit (excluding Windows IoT and Windows Embedded Compact)
Supported by PowerBuilder Runtime only:
Windows Server 2012 R2
Windows Server 2016
Windows Server 2019
If you decide to go on with the IDE on a windows server, and encounter an issue, to get support you will have to replicate that issue on a supported platform (currently for pb 2021 it is windows 8.1 and windows 10).
Here is a link with the equivallent information for PB 2019R3: System Requirements - - Installation Guide (appeon.com).
Andreas.