Hi Andrew;
FYI: From the PB 2017 installation manual ...
2. System Requirements
Before installing Appeon PowerBuilder 2017 Universal Edition, please ensure that your system meets the requirements below:
For installing PowerBuilder & PowerServer Toolkit
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Windows 10, Windows 8.1, or Windows 7
Supports Windows Server 2008/2012/2016 runtime only, not development.
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Microsoft .NET Framework 4.0
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(Optional) SAP SQL Anywhere 12.0, 16.0, or 17.0 (for running the PowerBuilder demos)
For installing PowerServer Mobile (.NET)
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(Recommended) Windows Server 2016, 2012 R2, or 2008 R2
(Optional) Windows 10/8.1/7
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Microsoft IIS 10, 8.0, 7.5, 7.0, or 6.0
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Microsoft .NET Framework 4.x
HTH
Regards ... Chris