Hi Billy,
In PowerServer 2021, you needed to deploy your project to a local IIS instance to be able to run it from the IDE. It being located in your IIS instance meant that you are able to run it and access is even if the IDE is closed (you still had to have the Web APIs running either in Kestrel or on IIS, depending on how you configured the ports). However, in PowerServer 2022 R2 and onwards, the IDE no longer requires a local IIS instance. When you run the project from the IDE, a local Kestrel server is created, which hosts both the Cloud App and the Web APIs. This Kestrel only lives as long as the Console Window that appears, so when you close it, the server is stopped. This means you are no longer able to access nor the Cloud App installation page, nor the Web APIs.
If you want it to behave like it used to, you should select External deployment, and specify your local IIS instance as a destination. Please note that you will need to have Web Deploy installed in your machine for this to work.
Please see the following documentation page which relates to this: https://docs.appeon.com/ps2022r2/Configuring_the_server_profile.html
Regards,
Francisco